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Hormonal replacement therapy after breast canceris It Safe? (HABITS) began in May 1997, to compare breast cancer survivors treated for at least 2 years with hormone therapy with treatment other than hormones. By September 2003, a total of 434 women had been randomized and, in December 2003, the steering committee of the HABITS study made the decision to stop the trial because there were 26 women in the treated group and 7 in the non-treated group with new breast cancer diagnoses.
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Changes in screening, endocervical sampling, nomenclature, and improvements in treatment likely explain the increased in situ cervical SCC incidence in white and black women. Increasing AIS incidence over the past 20 years in white women has not yet translated into a decrease in invasive AC incidence.
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In this article, Adams and Nelson integrate results from several disparate fields to advance the concept that autoimmune conditions resemble host vs graft disease and that the graft in many cases may be fetal or maternal cells that lodge in the host, namely the mother or fetus, respectively.
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A growing number of ED managers are coming to realize pain is much more than a physical symptom and taking a more holistic approach to pain can not only ease patient discomfort, but improve satisfaction.
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Schull MJ, Vermeulen M, Slaughter G, et al. Emergency department crowding and thrombolysis delays in acute myocardial infarction. Ann Emerg Med; in press.
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Influenza had a major impact on the nations hospitals this season, filling up intensive care units and leading to staff shortages. Currently, there is no standard that requires immunization of health care workers, but the Joint Commission requires hospitals to be in compliance with applicable laws and regulations. A vaccine against the H5N1 virus could be in clinical trials by this summer.
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The use of serum procalcitonin helps to differentiate bacterial from viral lower respiratory infections and may reduce the use of unnecessary antibiotics.
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The common and increasing practice of opioid treatment for chronic pain is reviewed. Randomized trials support this therapy, however the risk benefit decision is complicated by new evidence of hazards making this practice more difficult.
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Long-term treatment with aspirin is associated with a progressive diminution in platelet sensitivity to the drug.
